Cholesterol already has a vaccine, at least that’s what the latest edition of the European Heart Journal says. This is because researchers from the Medical University of Vienna managed to succeed in tests with laboratory mice.

The new vaccine is capable of reducing fatty deposits accumulated in the arteries that cause patients to take pills day after day to reduce the risk of heart attacks, as well as reducing the amount of bad cholesterol in the blood. According to experts, the vaccine will be ready in approximately six more years.


Scientists from the Hospital del Vall d’Hebron in Barcelona have demonstrated in a trial with rats the effectiveness of an oral treatment that reduces the consequences of myocardial infarction on heart function, even if the medication is administered one day after suffering the infarction .

The Cardiovascular Disease Research group of the Vall d’Hebron Research Institute (VHIR) led by David Gacía-Dorado has carried out this study with rats in which they have shown for the first time that the chronic inhibition of calpains (enzymes activated by the increase in intracellular calcium) is possible through an oral treatment that attenuates damage to the heart after an acute myocardial infarction.

It acts against the overactivation of calpains

The study, published in the journal Cardiovascular Research, used a transient coronary occlusion infarction model in rats to show that calpains remain overactivated during the weeks following an infarction and that this overactivation plays a fundamental role in the appearance of ventricular remodeling. adverse, a series of changes that affect the heart after the heart attack favoring the appearance of arrhythmias.

“Daily oral administration of a new calpain inhibitor -with properties that make it absorbable by the oral route- prevents this overactivation, reduces ventricular remodeling and improves contractile function 21 days after the infarction, even if treatment is started a little later. day after coronary occlusion”, summarized Dr. Javier Inserte, principal investigator of the VHIR Cardiovascular Diseases Research group.

The experienced treatment, according to Insert, decreases hypertrophy, fibrosis, and inflammation in the non-infarcted myocardium.

According to the researchers, the results suggest that this protective effect of calpain inhibition is due to the prevention of calpain’s effect on molecules that regulate gene expression.

“This study demonstrates for the first time that chronic calpain inhibition is possible by oral treatment and may represent a therapeutic strategy aimed at attenuating adverse remodeling and heart failure in patients surviving acute myocardial infarction,” he stressed. Garcia-Dorado.

Myocardial infarction, a condition generally caused by thrombotic occlusion of a coronary artery, is one of the main manifestations of ischemic heart disease.


Xavi Pascual, former Barça basketball coach and current Panathinaikos coach, will not have to undergo heart surgery, although he will visit a specialist in Barcelona. Initially there was a scare after the Greek website Sport 24 reported a heart condition that required a bypass.

Pascual, 44, felt unwell last Sunday and was hospitalized in Athens. There he underwent various tests that detected a heart problem. Yesterday Tuesday he was discharged. In Barcelona, ​​the coach of the Greek champion will receive a second opinion to determine the extent of his ailment.

“I want to thank everyone for their interest in me. I have gone to the hospital to undergo some medical tests, but I am fine. I will continue with my plans and tomorrow I will travel to Barcelona for the Euroleague coaches meeting. Thank you all for taking an interest in me”, declared the Catalan coach after leaving the hospital.

Xavi Pascual began coaching the Greek team this 2016/17 season, in which he has won the league and the cup, after developing his career at Barça, between 2008 and 2016.


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Instituto de Corazón de Querétaro 2018.

Instituto de Corazón de Querétaro 2018.